Changes in the microstructure of the trabecular meshwork may cause a decrease in outflow facility and an increase in IOP. 小梁網顯微結構的改變能夠引起房水流暢系數的降低而升高眼壓。
The effect was thought to be mediated via trabecular meshwork glucocorticoid receptors. 這種效應被認為是通過小梁網的糖皮質激素受體介導的。